This webinar describes analytical methods used for screening of extractables and leachables (E&L) in pharmaceutical packaging and product. Extractables analysis was performed by Direct TD-GCMS, while leachables by liquid injection-GCMS. Identification was carried out using NIST 14 Library and Shimadzu Polymer Additives Library. Instead of time-consuming solvent extraction procedure, a simpler Direct Thermal Desorption technique is used to perform extraction of the extractable compounds from polymer packaging. The result of extractables is compared with leachables analysis result from the product contained in the packaging.
Shimadzu (Asia Pacific) Pte Ltd
Cynthia started working with GC and GCMS in Shimadzu (Asia Pacific) in 2003, including various techniques such as headspace, SPME, thermal desorption and pyrolyzer. She has delivered numerous GC & GCMS training courses, participated in international seminars, workshops and conferences as well as developed application notes for Shimadzu (Asia Pacific).